Toxicology

Toxicology

Traditionally, toxicology is defined as the basic science of poisons. With the increasing understanding of how various agents can cause harm to humans and other organisms, a more descriptive definition of toxicology has been formulated as "the study of the adverse effects of chemical, physical, or biological agents on living organisms and the ecosystem, including the prevention and amelioration of such adverse effects."

These myriad adverse effects can assume diverse forms, ranging from immediate death to subtle changes not appreciated until sometime later (months to years), which may manifest at various levels within the body, such as an organ, a type of cell, or a specific biochemical pathway. With the progressive understanding of how toxic agents damage the body, it is now known that various observable changes in anatomy or bodily functions result from previously unrecognized changes in specific biochemicals within the body.

Scientists at Provictoire Research (PR) are engaged in mechanistic considerations and translational toxicology research, including human health and ecological risk assessments.